Polynucleotide Skin Booster in the heart of Gerrards Cross, Buckinghamshire for Regenerated, Youthful Skin

Advanced bio-regenerative treatment using polynucleotides to repair damaged skin at a cellular level, stimulating collagen production and deep hydration for naturally healthier, more resilient skin

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Polynucleotide skin booster treatment

What is Polynucleotide Skin Booster?

Polynucleotides (PNs) are naturally derived DNA fragments obtained from purified salmon DNA (PDRN). When injected into the skin, they act as powerful bio-stimulators that activate your body's own repair and regeneration processes. This next-generation skin booster goes beyond simple hydration — it fundamentally improves skin quality by repairing cellular damage and stimulating the production of new collagen and elastin.

Dr. Shaleen uses polynucleotide therapy to address the root causes of skin ageing, not just the symptoms. By working at a cellular level, this treatment repairs damaged tissue, reduces inflammation, improves elasticity, and restores a youthful, healthy glow that radiates from within.

Key Benefits:

  • Bio-regeneration at a cellular level
  • Stimulates collagen and elastin production
  • Repairs and protects damaged skin
  • Deep, long-lasting hydration
  • Anti-inflammatory and antioxidant properties
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How Polynucleotides Work The Science Behind the Treatment

Polynucleotides harness your body's natural repair mechanisms to rejuvenate skin from within

Cell Regeneration

Polynucleotides activate fibroblasts — the cells responsible for producing collagen, elastin, and hyaluronic acid — to regenerate and repair ageing skin.

Anti-Inflammatory Action

PNs possess potent anti-inflammatory properties that calm irritated skin, reduce redness, and create the ideal environment for healing.

Deep Hydration

Polynucleotides attract and bind water molecules at a deep dermal level, providing intense, long-lasting hydration that plumps the skin from within.

DNA Repair

As DNA fragments, polynucleotides provide the building blocks needed for cellular DNA repair, helping to reverse damage caused by UV exposure and ageing.

Collagen Stimulation

By activating fibroblast growth factors, polynucleotides significantly boost the production of new collagen for firmer, more elastic skin.

Free Radical Scavenging

Antioxidant properties neutralise free radicals and protect skin cells from oxidative stress and environmental damage.

Benefits of Polynucleotide Skin Booster

Transform your skin with bio-regenerative rejuvenation

Visible Improvements:

  • Improved skin elasticity and firmness
  • Deep, lasting hydration from within
  • Reduced fine lines and wrinkles
  • Smoother, more refined skin texture
  • Diminished dark circles under the eyes
  • Repaired sun-damaged and stressed skin
  • Reduced redness and inflammation
  • Restored skin radiance and luminosity
  • Effective for all skin types
  • Suitable for face, neck, décolletage, and under-eye area

What to Expect

Treatment

Precise micro-injections or cannula technique delivering polynucleotides into the dermal layer

Treatment Time

30-45 minutes including preparation

Downtime

Minimal - slight redness and swelling for 24-48 hours

Results

Initial improvement within days, optimal results at 4-8 weeks

Treatment Course

Initial course of 2-3 treatments, 3-4 weeks apart

Duration

Results last 6-12 months with maintenance treatments

How Polynucleotide Treatment Works

Your journey to regenerated, naturally youthful skin

~ 1 ~
Consultation & Skin Analysis

Dr. Shaleen will conduct a thorough skin assessment, discussing your concerns, skin history, and aesthetic goals. She'll evaluate your skin quality and determine whether polynucleotide treatment is the ideal option for your needs.

~ 2 ~
Preparation

Your skin will be thoroughly cleansed and a topical numbing cream applied to ensure maximum comfort during the treatment. The area will be prepared and marked for precise injection placement.

~ 3 ~
Injection Technique

Dr. Shaleen will use either a series of micro-injections or a cannula technique to deliver the polynucleotide solution into the dermal layer of your skin. The technique is tailored to the treatment area and your specific concerns.

~ 4 ~
Post-Treatment Care

A soothing serum or cooling mask may be applied to calm the skin. Dr. Shaleen will provide detailed aftercare instructions to optimise your results and support the healing process.

~ 5 ~
Bio-Regeneration Phase

Over the following weeks, the polynucleotides activate your fibroblasts, stimulating the production of new collagen, elastin, and hyaluronic acid. Your skin progressively improves in texture, firmness, and hydration.

~ 6 ~
Treatment Course

For optimal results, an initial course of 2-3 treatments is recommended, spaced 3-4 weeks apart. Maintenance treatments every 6-12 months will help sustain your rejuvenated results.

Am I a Good Candidate for Polynucleotide Treatment?

Discover if polynucleotide skin booster is right for you

You're a good candidate if you...

  • Want to improve overall skin quality and elasticity
  • Have thin, crepey, or dehydrated skin
  • Are concerned about dark circles under the eyes
  • Have sun-damaged or photo-aged skin
  • Seek a natural, bio-regenerative approach to skin rejuvenation
  • Are in generally good health
  • Have realistic expectations about results

Treatment may not be suitable if you...

  • Are pregnant or breastfeeding
  • Have an active skin infection or inflammation in the treatment area
  • Have a known allergy to fish or salmon-derived products
  • Have autoimmune or bleeding disorders
  • Are on immunosuppressive therapy
  • Have had recent facial surgery or laser treatments
  • Are taking certain medications (discuss with Dr. Shaleen)

Not sure if polynucleotide treatment is right for you?

Book a consultation with Dr. Shaleen to discuss your skin concerns and treatment options.

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Aftercare Guidelines

Follow these guidelines to maximise your results and ensure optimal healing

First 24 Hours

  • Avoid touching your face
    Keep hands away from treated areas to prevent infection
  • No makeup
    Allow injection sites to heal before applying cosmetics
  • Avoid exercise
    Skip strenuous physical activity and heavy sweating
  • Stay cool
    Avoid heat exposure including saunas, steam rooms, and hot baths
  • Sleep elevated
    Use an extra pillow to keep your head elevated and reduce swelling

First Week

  • Gentle skincare only
    Use mild, non-irritating cleansers and moisturisers
  • Avoid active ingredients
    Skip retinoids, AHAs, BHAs, and vitamin C for 5-7 days
  • No facial treatments
    Postpone facials, peels, microneedling, or laser treatments for 2 weeks
  • Sun protection is essential
    Apply SPF 30+ daily and avoid direct sun exposure
  • Limit alcohol
    Alcohol can increase swelling and dehydration

What You Should Do

  • Stay hydrated
    Drink plenty of water to support skin hydration and healing
  • Apply ice packs
    Use cold compresses to reduce swelling if needed
  • Moisturise regularly
    Keep skin well-hydrated with gentle moisturisers
  • Follow prescribed skincare
    Use any products recommended by Dr. Shaleen
  • Be patient
    Bio-regenerative results develop gradually over 4-8 weeks

Common Side Effects

These are normal and typically resolve within a few days:

  • Redness and swelling
    Usually subsides within 24-48 hours
  • Small bumps or papules
    Visible for 1-3 days at injection sites
  • Minor bruising
    Can occur; typically resolves within a week
  • Tenderness
    Mild sensitivity at treatment areas
  • Slight itching
    As the skin heals and regenerates

Contact Dr Shaleen immediately if you experience severe pain, excessive swelling, or signs of infection.

Follow-Up & Next Treatment

Your second treatment is typically scheduled 3-4 weeks after the first. Dr. Shaleen will assess your skin's response and adjust the treatment plan as needed. Complete the initial course of 2-3 treatments for optimal, long-lasting results, then maintain with treatments every 6-12 months.

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Why Choose Dr Shaleen for Polynucleotide Treatment?

Medical Expertise

Dr. Shaleen is a qualified GP with advanced training in aesthetic medicine and bio-regenerative skin treatments, ensuring safe, effective results.

Precision Technique

Meticulous injection technique tailored to your unique skin needs, ensuring even distribution for natural, harmonious results.

Personalised Treatment Plans

Every treatment is customised to your specific skin concerns, type, and aesthetic goals for optimal outcomes.

Frequently Asked Questions

Everything you need to know about polynucleotide skin booster treatment

Polynucleotides are long chains of nucleotides — the building blocks of DNA. The polynucleotides used in aesthetic treatments are derived from purified salmon DNA (PDRN - Polydeoxyribonucleotide). Through an extensive purification process, all proteins and potential allergens are removed, leaving only the bio-active DNA fragments that stimulate your skin's natural repair and regeneration processes.

While traditional skin boosters like hyaluronic acid primarily hydrate the skin, polynucleotides work at a deeper, cellular level. They activate fibroblasts to produce new collagen, elastin, and hyaluronic acid naturally. They also repair DNA damage, reduce inflammation, and scavenge free radicals. This bio-regenerative approach doesn't just improve the appearance of your skin — it genuinely improves skin health from within.

Most patients report minimal discomfort. A topical numbing cream is applied before the procedure to maximise comfort. You may feel small pinpricks during the injections, but the treatment is generally well-tolerated. For the under-eye area, Dr. Shaleen may use a cannula technique which many patients find even more comfortable than needle injections.

You may notice an initial improvement in skin hydration and glow within a few days. However, polynucleotide treatment works by stimulating your body's own regenerative processes, so the most significant improvements develop over 4-8 weeks as new collagen is produced. Results continue to improve throughout your treatment course, with the best outcomes seen after completing all sessions.

An initial course of 2-3 treatments is recommended, spaced 3-4 weeks apart, to achieve optimal results. After the initial course, maintenance treatments every 6-12 months will help sustain your improvements. Dr. Shaleen will create a personalised treatment plan based on your specific skin condition and goals.

Yes! Polynucleotide treatment is particularly effective for the delicate under-eye area. The bio-regenerative and anti-inflammatory properties help to thicken thin skin, improve hydration, reduce pigmentation, and stimulate collagen production in this notoriously difficult-to-treat area. Many patients see a visible reduction in dark circles and hollowing after their treatment course.

Yes! Polynucleotide treatment works beautifully alongside other aesthetic treatments. It can be combined with NCTF skin boosters, anti-wrinkle injections, dermal fillers, or microneedling as part of a comprehensive rejuvenation plan. However, treatments should be properly spaced to allow optimal healing. Dr. Shaleen will advise on the best treatment combination and timing for your specific needs.

Although polynucleotides are derived from salmon DNA, the purification process removes virtually all proteins and potential allergens. However, if you have a known severe fish allergy, it is important to discuss this with Dr. Shaleen during your consultation. She will assess your suitability and may recommend an alternative treatment if necessary. Your safety is always the top priority.

Have more questions about polynucleotide treatment?

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Ready to Regenerate Your Skin?

Book your polynucleotide skin booster consultation with Dr Shaleen and discover the power of bio-regenerative rejuvenation.

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