Polynucleotide Skin Booster in the heart of Gerrards Cross, Buckinghamshire for Regenerated, Youthful Skin
Advanced bio-regenerative treatment using polynucleotides to repair damaged skin at a cellular level, stimulating collagen production and deep hydration for naturally healthier, more resilient skin
What is Polynucleotide Skin Booster?
Polynucleotides (PNs) are naturally derived DNA fragments obtained from purified salmon DNA (PDRN). When injected into the skin, they act as powerful bio-stimulators that activate your body's own repair and regeneration processes. This next-generation skin booster goes beyond simple hydration — it fundamentally improves skin quality by repairing cellular damage and stimulating the production of new collagen and elastin.
Dr. Shaleen uses polynucleotide therapy to address the root causes of skin ageing, not just the symptoms. By working at a cellular level, this treatment repairs damaged tissue, reduces inflammation, improves elasticity, and restores a youthful, healthy glow that radiates from within.
- Bio-regeneration at a cellular level
- Stimulates collagen and elastin production
- Repairs and protects damaged skin
- Deep, long-lasting hydration
- Anti-inflammatory and antioxidant properties
How Polynucleotides Work The Science Behind the Treatment
Polynucleotides harness your body's natural repair mechanisms to rejuvenate skin from within
Cell Regeneration
Polynucleotides activate fibroblasts — the cells responsible for producing collagen, elastin, and hyaluronic acid — to regenerate and repair ageing skin.
Anti-Inflammatory Action
PNs possess potent anti-inflammatory properties that calm irritated skin, reduce redness, and create the ideal environment for healing.
Deep Hydration
Polynucleotides attract and bind water molecules at a deep dermal level, providing intense, long-lasting hydration that plumps the skin from within.
DNA Repair
As DNA fragments, polynucleotides provide the building blocks needed for cellular DNA repair, helping to reverse damage caused by UV exposure and ageing.
Collagen Stimulation
By activating fibroblast growth factors, polynucleotides significantly boost the production of new collagen for firmer, more elastic skin.
Free Radical Scavenging
Antioxidant properties neutralise free radicals and protect skin cells from oxidative stress and environmental damage.
Benefits of Polynucleotide Skin Booster
Transform your skin with bio-regenerative rejuvenation
- Improved skin elasticity and firmness
- Deep, lasting hydration from within
- Reduced fine lines and wrinkles
- Smoother, more refined skin texture
- Diminished dark circles under the eyes
- Repaired sun-damaged and stressed skin
- Reduced redness and inflammation
- Restored skin radiance and luminosity
- Effective for all skin types
- Suitable for face, neck, décolletage, and under-eye area
What to Expect
Precise micro-injections or cannula technique delivering polynucleotides into the dermal layer
30-45 minutes including preparation
Minimal - slight redness and swelling for 24-48 hours
Initial improvement within days, optimal results at 4-8 weeks
Initial course of 2-3 treatments, 3-4 weeks apart
Results last 6-12 months with maintenance treatments
How Polynucleotide Treatment Works
Your journey to regenerated, naturally youthful skin
Consultation & Skin Analysis
Dr. Shaleen will conduct a thorough skin assessment, discussing your concerns, skin history, and aesthetic goals. She'll evaluate your skin quality and determine whether polynucleotide treatment is the ideal option for your needs.
Preparation
Your skin will be thoroughly cleansed and a topical numbing cream applied to ensure maximum comfort during the treatment. The area will be prepared and marked for precise injection placement.
Injection Technique
Dr. Shaleen will use either a series of micro-injections or a cannula technique to deliver the polynucleotide solution into the dermal layer of your skin. The technique is tailored to the treatment area and your specific concerns.
Post-Treatment Care
A soothing serum or cooling mask may be applied to calm the skin. Dr. Shaleen will provide detailed aftercare instructions to optimise your results and support the healing process.
Bio-Regeneration Phase
Over the following weeks, the polynucleotides activate your fibroblasts, stimulating the production of new collagen, elastin, and hyaluronic acid. Your skin progressively improves in texture, firmness, and hydration.
Treatment Course
For optimal results, an initial course of 2-3 treatments is recommended, spaced 3-4 weeks apart. Maintenance treatments every 6-12 months will help sustain your rejuvenated results.
Am I a Good Candidate for Polynucleotide Treatment?
Discover if polynucleotide skin booster is right for you
You're a good candidate if you...
- Want to improve overall skin quality and elasticity
- Have thin, crepey, or dehydrated skin
- Are concerned about dark circles under the eyes
- Have sun-damaged or photo-aged skin
- Seek a natural, bio-regenerative approach to skin rejuvenation
- Are in generally good health
- Have realistic expectations about results
Treatment may not be suitable if you...
- Are pregnant or breastfeeding
- Have an active skin infection or inflammation in the treatment area
- Have a known allergy to fish or salmon-derived products
- Have autoimmune or bleeding disorders
- Are on immunosuppressive therapy
- Have had recent facial surgery or laser treatments
- Are taking certain medications (discuss with Dr. Shaleen)
Aftercare Guidelines
Follow these guidelines to maximise your results and ensure optimal healing
First 24 Hours
Avoid touching your face. No makeup — allow injection sites to heal before applying cosmetics. Avoid exercise. Stay cool — avoid heat exposure including saunas, steam rooms, and hot baths. Sleep elevated to reduce swelling.
First Week
Gentle skincare only. Avoid active ingredients for 5-7 days. No facial treatments for 2 weeks. Sun protection is essential — apply SPF 30+ daily. Limit alcohol.
What You Should Do
Stay hydrated. Apply ice packs if needed. Moisturise regularly. Follow prescribed skincare. Be patient — bio-regenerative results develop gradually over 4-8 weeks.
Common Side Effects
Redness and swelling usually subsides within 24-48 hours. Small bumps or papules visible for 1-3 days at injection sites. Minor bruising can occur. Tenderness and slight itching as the skin heals are normal. Contact Dr Shaleen immediately if you experience severe pain, excessive swelling, or signs of infection.
Follow-Up & Next Treatment
Your second treatment is typically scheduled 3-4 weeks after the first. Dr. Shaleen will assess your skin's response and adjust the treatment plan as needed. Complete the initial course of 2-3 treatments for optimal, long-lasting results, then maintain with treatments every 6-12 months.
Why Choose Dr Shaleen for Polynucleotide Treatment?
Medical Expertise
Dr. Shaleen is a qualified GP with advanced training in aesthetic medicine and bio-regenerative skin treatments, ensuring safe, effective results.
Precision Technique
Meticulous injection technique tailored to your unique skin needs, ensuring even distribution for natural, harmonious results.
Personalised Treatment Plans
Every treatment is customised to your specific skin concerns, type, and aesthetic goals for optimal outcomes.
Frequently Asked Questions
Polynucleotides are long chains of nucleotides — the building blocks of DNA. The polynucleotides used in aesthetic treatments are derived from purified salmon DNA (PDRN - Polydeoxyribonucleotide). Through an extensive purification process, all proteins and potential allergens are removed, leaving only the bio-active DNA fragments that stimulate your skin's natural repair and regeneration processes.
While traditional skin boosters like hyaluronic acid primarily hydrate the skin, polynucleotides work at a deeper, cellular level. They activate fibroblasts to produce new collagen, elastin, and hyaluronic acid naturally. They also repair DNA damage, reduce inflammation, and scavenge free radicals. This bio-regenerative approach doesn't just improve the appearance of your skin — it genuinely improves skin health from within.
Most patients report minimal discomfort. A topical numbing cream is applied before the procedure to maximise comfort. You may feel small pinpricks during the injections, but the treatment is generally well-tolerated. For the under-eye area, Dr. Shaleen may use a cannula technique which many patients find even more comfortable than needle injections.
You may notice an initial improvement in skin hydration and glow within a few days. However, polynucleotide treatment works by stimulating your body's own regenerative processes, so the most significant improvements develop over 4-8 weeks as new collagen is produced. Results continue to improve throughout your treatment course, with the best outcomes seen after completing all sessions.
An initial course of 2-3 treatments is recommended, spaced 3-4 weeks apart, to achieve optimal results. After the initial course, maintenance treatments every 6-12 months will help sustain your improvements. Dr. Shaleen will create a personalised treatment plan based on your specific skin condition and goals.
Yes! Polynucleotide treatment is particularly effective for the delicate under-eye area. The bio-regenerative and anti-inflammatory properties help to thicken thin skin, improve hydration, reduce pigmentation, and stimulate collagen production in this notoriously difficult-to-treat area. Many patients see a visible reduction in dark circles and hollowing after their treatment course.
Yes! Polynucleotide treatment works beautifully alongside other aesthetic treatments. It can be combined with NCTF skin boosters, anti-wrinkle injections, dermal fillers, or microneedling as part of a comprehensive rejuvenation plan. However, treatments should be properly spaced to allow optimal healing. Dr. Shaleen will advise on the best treatment combination and timing for your specific needs.
Although polynucleotides are derived from salmon DNA, the purification process removes virtually all proteins and potential allergens. However, if you have a known severe fish allergy, it is important to discuss this with Dr. Shaleen during your consultation. She will assess your suitability and may recommend an alternative treatment if necessary. Your safety is always the top priority.
Ready to Regenerate Your Skin?
Book your polynucleotide skin booster consultation with Dr Shaleen and discover the power of bio-regenerative rejuvenation.
Book Your Consultation Today